Discover the science of human performance through engaging stories and research-driven insights in our Alliance Playbook
Wu Tsai Human Performance Alliance at UC San Diego 2024 Research SymposiumAuthor: Alina Mullen, Industry and Community Liaison for Wu Tsai Human Performance Alliance
On Thursday, October 10, 2024 Wu Tsai Human Performance Alliance (WTHPA) at UC San Diego hosted its annual research symposium at Franklin Antonio Hall. The event featured keynote speaker Matt Ustaszewski, UCSD Men’s Water Polo & Team USA Olympic Coach and 20 trainee presentations from 10 of our WTHPA primary investigators’ labs, including guest WTHPA members from Salk Institute for Biological Studies. The trainee presentations involved undergraduates, graduates and doctoral students as well as postdocs and research coordinators.
We were proud to present awards for best presentation awards to:
- Juliette Hamid, Undergraduate Researcher, UC San Diego Prof. Padmini Rangamani “The Interplay between Store-Operated Calcium Entry and Cross-Bridge Cycling in Muscle Fibers during Exercise”
- Liam Fitzgerald, Ph.D. Researcher, UC San Diego Prof. Simon Schenk “Skeletal muscle mitochondrial function does not exhibit circadian regulation at a transcriptional, translational, or functional level in mice”
- Laura von Rosmalen, Postdoc, Salk Prof. Satchin Panda “A mouse model of relative energy deficiency in sport”
Over 50 researchers were in attendance! We were very impressed with the quality of the presentations and thank them for the vibrant discussions that ensued!
Dr. McCulloch and Dr. Ward are editing a special collection for Scientific Reports on Myogenesis
Myogenesis is the process by which muscle tissue forms and develops, and is crucial for the growth, repair, and regeneration of the musculoskeletal system. Key regulatory factors such as MyoD and Myogenin play essential roles in controlling the differentiation from mesodermal cells and satellite cells through myoblasts, myotubes and into mature muscle fibres.
This Collection welcomes original research investigating myogenesis and its implications in health and disease. Submissions from relevant areas of biology, biomedical engineering and clinical medicine are encouraged.
Submissions can be submitted here before June 26th, 2025.
Moonshot
New Modeling Publication from the Multiscale Athlete Moonshot! June 06, 2024
Dr. Kim Cooper’s Groundbreaking Work with the Moonshot! December 01, 2021
Innovation Hub
New Publication from the Innovation Hub!
December 01, 2022
News from the Innovation Hub!
January 14, 2022
Innovation Hub in the News!
July 16, 2021
Dr. Ward’s research on stem cell therapies! August 26, 2024
Recent Publications
– Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training. Experimental Physiology, 1-17 Fowler A, Knaus KR, Khuu S, Khalilimeybodi A, Schenk S, Ward SR, Fry AC, Rangamani P, McCulloch A D (PMID: https://pubmed.ncbi.nlm.nih.gov/38643471/)
– Mechanisms underlying divergent relationships between Ca2+ and YAP/TAZ signaling Khalilimeybodi, S.I. Fraley, P. Journal of Physiology 04 December 2022 (PMID: https://pubmed.ncbi.nlm.nih.gov/36463416/)
– Rescue of Alzheimer’s disease phenotype in a mouse model by transplantation of wild-type hematopoietic stem and progenitor cells Mishra P, Silva A, Sharma J, Nguyen J, Pizzo DP, Hinz D, Sahoo D, Cherqui S. Cell Rep. 2023 Aug 29;42(8):112956. doi: 10.1016/j.celrep.2023.112956. Epub 2023 Aug 8.(PMID: https://pubmed.ncbi.nlm.nih.gov/37561625/)
– Machine learning identifies signatures of macrophage reactivity and tolerance that predict disease outcomes Ghosh P, Sinha S, Katkar G D, Vo D, Taheri S, Dang D, Das S, Sahoo D EBioMedicine. 2023 Aug:94:104719. doi: 10.1016/j.ebiom.2023.104719. Epub 2023 Jul 27.(PMID: https://pubmed.ncbi.nlm.nih.gov/37516087/)
– Computational modeling establishes mechanotransduction as a potent entrainment cue for the mammalian circadian clock E. A. Francis, P. Rangamani 2023.10.09.561563 (PMID: https://pubmed.ncbi.nlm.nih.gov/39140137/)
– Network model of skeletal muscle cell signaling predicts differential responses to endurance and resistance exercise training Fowler A, Knaus K R, Khuu S, Khalilimeybodi A, Schenk S, Ward S, Fry A C, Rangamani P, McCulloch A D 2023 J Physiol (Lond.) (PMID: https://pubmed.ncbi.nlm.nih.gov/38643471/)
– Differential Sensitivity to Longitudinal and Transverse Stretch Mediates Transcriptional Responses in Mouse Neonatal Ventricular Myocytes Cao S, Buchholz K, Tan P, Stowe J, Wang A, Fowler A, Knaus K, Khalilimeybodi A, Zambon A, Omens J, Saucerman J, McCulloch A 2023 AJP (PMID: https://pubmed.ncbi.nlm.nih.gov/38063811/)
– Macrophages on the run: Exercise balances macrophage polarization for improved health Voskoboynik Y, McCulloch A, Sahoo D 2024 (DOI: https://www.sciencedirect.com/science/article/pii/S2212877824001893?via%3Dihub)
– Visual Performance and Sports: A Scoping Review. Journal of Sports and Exercise Psychology Lochhead L, Feng J, Laby D M, Appelbaum L G (PMID: https://pubmed.ncbi.nlm.nih.gov/38815973/ )
– Strength, speed, and anthropometric predictors of in-game batting performance in baseball Kohn J N, Lochhead L, Feng J, Bobb R, Appelbaum L G. Journal of Sports Science.(PMID: https://pubmed.ncbi.nlm.nih.gov/38833336/)
– The physiology of intraoperative error: using electrokardiograms to understand operator performance during robot-assisted surgery simulations D’Ambrosia C, Aronoff-Spencer E, Huang E Y, Goldhaber N H, Jacobsen G R, Sandler B, Horgan S, Broderick R C, Christensen H, Appelbaum L G (PMID: https://pubmed.ncbi.nlm.nih.gov/36862171/)
– Dispase/Collagenase cocktail allows for co-isolation of satellite cells and fibro-adipogenic progenitors from human skeletal muscle Balayan, A., DeBoutray, M., Molley, T.G., Ruoss, S., Maceda, M., Sevier, A., Robertson, C.M., Ward, S.R., Engler, A.J. Am J Physiol-Cell Physiol, 2024. 326 (4): C1193-C1202. (PMID: https://pubmed.ncbi.nlm.nih.gov/38581669/)
– Comparative single cell transcriptional and proteomic atlas of clinical-grade injectable mesenchymal source tissues Ruoss, S., Nasamran, C.A., Ball, S.T., Chen, J.L., Halter, K.N., Bruno, K.A., Whisenant, T.C., Parekh, J.N., Dorn,S.N., Esparza, M.C, Bremner, S.N.,. Fisch, K.M., Engler, A.J., Ward, S.R. Science Advances. (PMID: https://pubmed.ncbi.nlm.nih.gov/38996032/)
– Intrinsic skeletal muscle function and contraction-stimulated glucose uptake do not vary by time-of-day in mice. Fitzgerald LS, Bremner SN, Ward SR, Cho Y, Schenk S. eLife. (PMID: https://pubmed.ncbi.nlm.nih.gov/38798320/)
– An Integrated Approach to Musculoskeletal Performance, Disease, and Recovery. Physical Therapy Journal, Lawrence R, Ludewig P, and Ward SR Dec 1;101(12), 2021. (PMID: https://pubmed.ncbi.nlm.nih.gov/34636897/)
– Spatial transcriptomics to explore regional differences within pathological muscle tissue in the pre-clinical rabbit model of rotator cuff tear. Journal of Orthopaedic Surgery and Research Ruoss S, Esparza MC, Vasquez-Bolanos LS, Nasamran CA, Fisch KM, Engler AJ, Ward SR. Journal of Orthopaedic Surgery and Research, Oct 4:17(1):440, 2022. (PMID: https://pubmed.ncbi.nlm.nih.gov/36195913/)
– Psychomotor and visual skills underlying position specialization in 1352 elite youth baseball players Ho J, Liu S, Feng Z, Appelbaum LG (PMID: https://pubmed.ncbi.nlm.nih.gov/36656847/)
– The Deep Region of the Supraspinatus Muscle Is Architecturally Distinct. Hyman S, Norman M, Sendek G, Powell J, Kirchberg T, Berry D, Lane J, Singh A, Ward S, Wu I OJSM 2023. (PMID: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392267/)
– Predictors of batting and pitching performance in the USA Baseball Prospect Development Pipeline Feng, Z., Lochhead, L., Kohn, J.N., and Appelbaum, L.G. Sports Biomechanics (PMID:https://pubmed.ncbi.nlm.nih.gov/38190251/)
– Network model of skeletal muscle cell signaling predicts differential responses to endurance and resistance exercise training Fowler A, Knaus K R, Khuu S, Khalilimeybodi A, Schenk S, Ward S, Fry A C, Rangamani P, McCulloch A D 2023 J Physiol (Lond.) (PMID: https://pubmed.ncbi.nlm.nih.gov/38643471/)